{"id":35,"date":"2026-08-06T09:12:42","date_gmt":"2026-08-06T09:12:42","guid":{"rendered":"https:\/\/www.peptidelab.co.il\/product\/%d7%9e%d7%95%d7%a6%d7%a8-%d7%93%d7%95%d7%92%d7%9e%d7%94-09-demo-item-i-935\/"},"modified":"2026-10-30T12:10:30","modified_gmt":"2026-10-30T12:10:30","slug":"mots-c","status":"publish","type":"product","link":"https:\/\/www.peptidelab.co.il\/en\/product\/mots-c\/","title":{"rendered":"MOTS-c"},"content":{"rendered":"<p><strong>MOTS-c<\/strong> is a mitochondrial peptide studied in the contexts of metabolism, the AMPK pathway, physical exercise and aging, and intended <strong>for laboratory research only (Research Use Only)<\/strong>.<\/p>\n<h2>What is MOTS-c?<\/h2>\n<p>MOTS-c is a short 16-amino-acid peptide encoded in a region of the mitochondrial DNA (the 12S rRNA sequence), belonging to the mitochondrial-derived peptides family. Its full name is Mitochondrial Open Reading Frame of the 12S rRNA-c.<\/p>\n<h2>MOTS-c in research \u2014 mechanism &amp; evidence<\/h2>\n<p>The research interest stems from the view that the mitochondrion is not merely a source of energy but also a signaling factor. Research has examined possible involvement of MOTS-c in the AMPK pathway, in metabolic homeostasis and in the response to physical exercise \u2014 mainly in animal models.<\/p>\n<h3>Sources &amp; further information<\/h3>\n<p>For a full list of sources and studies, see the \"More info\" tab on this page, or browse<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=MOTS-c\" target=\"_blank\" rel=\"noopener\">MOTS-c studies on PubMed<\/a>.<\/p>\n<h2>Reconstitution and storage of MOTS-c<\/h2>\n<p>MOTS-c (sometimes also written &quot;MOTS c&quot;) comes as a freeze-dried powder. Before use in research, it is reconstituted with <a href=\"\/en\/product\/bac-water\/\">bacteriostatic water<\/a>; the dilution ratio determines the concentration \u2014 for an exact calculation see the <a href=\"\/en\/calculator\/\">our dilution calculator<\/a>. The dry powder is stored refrigerated and protected from light, and after reconstitution refrigerated storage is recommended.<\/p>\n<h2>FAQ \u2014 MOTS-c<\/h2>\n<p><strong>What is MOTS-c?<\/strong><br \/>A mitochondrial-derived peptide (16 amino acids) studied in the context of metabolism, the AMPK pathway and aging; intended for research use only.<\/p>\n<p><strong>Why is MOTS-c studied?<\/strong><br \/>Mainly in a metabolic context, insulin sensitivity and response to physical activity \u2014 most evidence comes from animal models.<\/p>\n<p><strong>How is MOTS-c reconstituted?<\/strong><br \/>Add bacteriostatic water according to the desired concentration; for calculation see <a href=\"\/en\/calculator\/\">our dilution calculator<\/a>.<\/p>\n<p>For additional peptides in a metabolic and weight-loss context, see the <a href=\"\/en\/product-category\/peptides-weight-loss\/\">Weight loss category<\/a>.<\/p>\n<p><em>Disclaimer: all products are intended for laboratory research only. Purchase is permitted from age 18 and up.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Research reference material \u2014 a mitochondrial-derived peptide (16 amino acids), studied in the context of the AMPK pathway and metabolism. Lyophilised powder, high purity. Research use only.<\/p>","protected":false},"featured_media":1192,"comment_status":"open","ping_status":"closed","template":"","meta":{"_joinchat":[]},"product_brand":[],"product_cat":[26,32],"product_tag":[],"class_list":["post-35","product","type-product","status-publish","has-post-thumbnail","product_cat-peptides","product_cat-peptides-weight-loss","first","instock","shipping-taxable","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/product\/35","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/comments?post=35"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/media\/1192"}],"wp:attachment":[{"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/media?parent=35"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/product_brand?post=35"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/product_cat?post=35"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.peptidelab.co.il\/en\/wp-json\/wp\/v2\/product_tag?post=35"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}